Diagnostic Accuracy of the Truenat MTB Plus Assay and Comparison with the Xpert MTB/RIF Assay to Detect Tuberculosis among Hospital Outpatients in Cameroon-Reference-Cited by-同舟云学术

Diagnostic Accuracy of the Truenat MTB Plus Assay and Comparison with the Xpert MTB/RIF Assay to Detect Tuberculosis among Hospital Outpatients in Cameroon

Published:2022-08-17 Issue:8 Volume:60 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Ngangue Yannick Russel¹^ORCID,Mbuli Cyrille¹^ORCID,Neh Angela¹,Nshom Emmanuel²³,Koudjou Armand²,Palmer Dennis²³,Ndi Norah Nyah²³,Qin Zhi Zhen⁴^ORCID,Creswell Jacob⁴^ORCID,Mbassa Vincent⁵,Vuchas Comfort¹^ORCID,Sander Melissa¹^ORCID

Affiliation:

1. Center for Health Promotion and Research, Bamenda, Cameroon

2. Cameroon Baptist Convention Health Services, Bamenda, Cameroon

3. Baptist Institute of Health Sciences, Bamenda, Cameroon

4. Stop TB Partnership, Geneva, Switzerland

5. National TB Program, Yaounde, Cameroon

Abstract

The Truenat MTB Plus assay is a rapid molecular test that has been recommended by the World Health Organization since 2020 as an initial test to detect tuberculosis (TB). The WHO highlighted the need to further evaluate assay performance to inform future recommendations, including in people living with HIV and compared to the Xpert MTB/RIF assay. We conducted a prospective evaluation of the diagnostic accuracy of the Truenat assay in Cameroon, a country with a high burden of HIV/TB.

Funder

Global Affairs Canada

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.00155-22

Reference32 articles.

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