Augmentation of interleukin-2 production and delayed hypersensitivity in mice infected with Mycobacterium bovis and fed a diet supplemented with vitamin A acetate

Author:

Colizzi V,Malkovsky M

Abstract

High-dose Mycobacterium bovis-infected mice fed a vitamin A acetate-supplemented diet developed a positive skin reaction to purified protein derivative of mycobacteria, and their spleen cells showed an increased IL-2 production in vitro.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference13 articles.

1. Vitamin A-induced nonspecific resistance to infection;Cohen B. E.;J. Infect. Dis.,1974

2. In vivo and in vitro administration of interleukin-2-containing preparation reverses T-cell unresponsiveness in Mycobacterium bovis BCG-infected mice;Colizzi V.;Infect. Immun.,1984

3. Suppressor cells induced by BCG release non-specific factors in vitro which inhibit DNA synthesis and interleukin-2 production;Colizzi V.;Immunology,1984

4. T-cell conditioned media reverse T-cell unresponsiveness in lepromatous leprosy;Haregewoin A.;Nature (London),1983

5. Stimulation of cell-mediated resistance in mice to infection with Listeria monocytogenes by vitamin A;Hof H.;Ann. Immunol. (Paris),1979

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