Mapping Simocyclinone D8 Interaction with DNA Gyrase: Evidence for a New Binding Site on GyrB
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, University of Padova, Via Marzolo, Padua 5-35131, Italy
2. Department of Biological Chemistry, John Innes Centre, Colney, Norwich NR4 7UH, United Kingdom
Abstract
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Link
https://journals.asm.org/doi/pdf/10.1128/AAC.00972-09
Reference38 articles.
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2. Ali, J. A., G. Orphanides, and A. Maxwell. 1995. Nucleotide binding to the 43-kilodalton N-terminal fragment of the DNA gyrase B protein. Biochemistry34:9801-9808.
3. Appelbaum, P. C., and P. A. Hunter. 2000. The fluoroquinolone antibacterials: past, present and future perspectives. Int. J. Antimicrob. Agents16:5-15.
4. Blandamer, M. J., B. Briggs, P. M. Cullis, A. P. Jackson, A. Maxwell, and R. J. Reece. 1994. Domain structure of Escherichia coli DNA gyrase as revealed by differential scanning calorimetry. Biochemistry33:7510-7516.
5. Quinolone-Mediated Bacterial Death
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