First Characterization of Fluoroquinolone Resistance in Streptococcus suis-Reference-Cited by-同舟云学术

First Characterization of Fluoroquinolone Resistance in Streptococcus suis

Published:2007-02 Issue:2 Volume:51 Page:777-782
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Escudero Jose Antonio¹,San Millan Alvaro¹,Catalan Ana¹,de la Campa Adela G.²,Rivero Estefania¹,Lopez Gema¹,Dominguez Lucas¹,Moreno Miguel Angel¹,Gonzalez-Zorn Bruno¹

Affiliation:

1. Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain

2. Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain

Abstract

ABSTRACT We have identified and sequenced the genes encoding the quinolone-resistance determining region (QRDR) of ParC and GyrA in fluoroquinolone-susceptible and -resistant Streptococcus suis clinical isolates. Resistance is the consequence of single point mutations in the QRDRs of ParC and GyrA and is not due to clonal spread of resistant strains or horizontal gene transfer with other bacteria.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00972-06

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