Author:
Gutmann L,Goldstein F W,Kitzis M D,Hautefort B,Darmon C,Acar J F
Abstract
Twelve Nocardia asteroides isolates were tested for their susceptibility to 46 antibiotics by the agar dilution method. N-Formimidoyl thienamycin was the most active of 22 beta-lactam antibiotics, inhibiting 11 of the 12 strains at 1 microgram/ml. Penicillins, including ureidopenicillins, showed poor activity. Cefotaxime, ceftriaxone, and especially cefuroxime had the best activities of the cephalosporins tested. Among the other antibiotics, amikacin and minocycline, respectively, inhibited all of the strains tested at 0.5 and 4 micrograms/ml.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference14 articles.
1. Pulmonary nocardiosis-therapy with minocycine and with erythromycin plus ampicillin;Bach M. D.;J. Am. Med. Assoc.,1973
2. Susceptibility of Nocardia asteroides to 45 antimicrobial agents in vitro;Bach M. C.;Antimicrob. Agents Chemother.,1973
3. Successful treatment of systemic nocardiosis with cotrimoxazole;Bayley S.;J. Infect. Dis.,1981
4. A method for determining in vitro drug susceptibilities of some Nocardia and;Caroll G. F.;Actinomadurae. Am. J. Clin. Pathol.,1977
5. In vitro susceptibility of Nocardia asteroides to N-formimidoyl thienamycin and several cephalosporins;Cynamon M. H.;Antimicrob. Agents Chemother.,1981
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