Author:
Binnicker Matthew J.,Espy Mark J.,Irish Cole L.,Vetter Emily A.
Abstract
We compared an FDA-cleared rapid (<20 min) PCR assay (Cobas Liat; Roche Diagnostics) to our routine influenza A and B real-time PCR assay (Simplexa Flu A/B & RSV Direct; Focus Diagnostics) using respiratory swabs (n= 197). The Cobas Liat influenza A and B assays demonstrated sensitivities of 99.2% (123/124) and 100% (23/23), respectively, while showing a specificity of 100% for each target.
Publisher
American Society for Microbiology
Reference6 articles.
1. Pandemic H1N1 and seasonal H3N2 influenza infection in the human population show different distributions of viral loads, which substantially affect the performance of rapid influenza tests;Virus Res,2011
2. Evaluation of 11 commercially available rapid influenza diagnostic tests–United States, 2011-2012;Centers for Disease Control and Prevention;MMWR Morb Mortal Wkly Rep,2012
3. Quantitative analysis of four rapid antigen assays for detection of pandemic H1N1 2009 compared with seasonal H1N1 and H3N2 influenza A viruses on nasopharyngeal aspirates from patients with influenza;J Virol Methods,2012
4. Comparison of real-time RT-PCR, shell vial culture, and conventional cell culture for the detection of the pandemic influenza A (H1N1) in hospitalized patients;Diagn Microbiol Infect Dis,2011
5. Evaluation of the Cepheid Xpert Flu assay for rapid identification and differentiation of influenza A, influenza A 2009 H1N1, and influenza B viruses;J Clin Microbiol,2012
Cited by
83 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献