Listeria monocytogenes ATCC 35152 and NCTC 7973 contain a nonhemolytic, nonvirulent variant

Author:

Pine L1,Weaver R E1,Carlone G M1,Pienta P A1,Rocourt J1,Goebel W1,Kathariou S1,Bibb W F1,Malcolm G B1

Affiliation:

1. Division of Bacterial Diseases, Centers for Disease Control, Atlanta, Georgia 30333.

Abstract

Listeria monocytogenes NCTC 7973 and this same strain deposited as ATCC 35152 contain two phenotypes: hemolytic virulent colonies and nonvirulent colonies that show no zones of hemolysis when streaked on heart infusion agar containing 5% rabbit blood. Results of examinations of these virulent and nonvirulent strains by investigators at the Centers for Disease Control, Atlanta, Ga., the Pasteur Institute, Paris, France, and the University of Würzburg, Federal Republic of Germany, support the conclusion that the avirulent strain is a nonhemolytic mutant of the virulent strain and that hemolysin is a virulence factor for L. monocytogenes.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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