Susceptibility of Clostridium ramosum to Antimicrobial Agents-Reference-Cited by-同舟云学术

Susceptibility of Clostridium ramosum to Antimicrobial Agents

Published:1974-06 Issue:6 Volume:5 Page:589-593
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Tally Francis P.¹²³,Armfield Ann Y.¹²³,Dowell V. R.¹²³,Kwok Yung-Yuan¹²³,Sutter Vera L.¹²³,Finegold Sydney M.¹²³

Affiliation:

1. Anaerobic Bacteriology Laboratory, Medical and Research Services, Veterans Administration, Wadsworth Hospital Center, Los Angeles, California 90073

2. Department of Medicine, UCLA School of Medicine, Los Angeles, California 90024

3. Bacteriology Section, Center for Disease Control, Atlanta, Georgia 30333

Abstract

The susceptibility of 49 strains of Clostridium ramosum to 10 antibiotics was determined by agar dilution and disk diffusion tests. Results showed that, among the anaerobes, C. ramosum is second only to Bacteroides fragilis in its resistance to antimicrobial agents. All strains were susceptible to penicillin, carbenicillin, chloramphenicol, vancomycin, and metronidazole at readily achievable blood levels. Most strains (83%) were susceptible to erythromycin. There was a high level of resistance to clindamycin in 16% of the strains. All isolates were resistant to rifampin and gentamicin, and most were resistant to lincomycin. Assessment of susceptibility by measurement of inhibition zone diameters with disk diffusion tests was not satisfactory.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.5.6.589

Reference19 articles.

1. Attebery H. R. V. L. Sutter and S. M. Finegold. 1974. Normal human intestinal flora. In A. Balows et al. (ed.) Anaerobic bacterial diseases: Proc. of a Conference held at CDC Atlanta Ga. November 1972. Charles C Thomas Co. Springfield Ill.

2. Treatment of anaerobic infections with lincomycin and clindamycin;Bartlett J. G.;N. Engl. J. Med.,1972

3. Antibiotic susceptibility testing by a single disc method;Bauer A. W.;Amer. J. Clin. Pathol.,1966

4. Antibiotic susceptibility testing of bacteroides;Bodner S. J.;Antimicrob. Ag. Chemother.,1972

5. Pharmacokinetic studies of clindamycin phosphate;De Haan R. M.;J. Clin. Pharmacol.,1973

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