Affiliation:
1. Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799.
Abstract
Detection of group B streptococcus (GBS) antigen in urine by latex particle agglutination (LPA) may facilitate the rapid diagnosis of GBS sepsis. We sought to compare three commercial LPA assays with specimens that were spiked with type-specific antigen, group-specific antigen, or type III organisms. There were sensitivity differences between the assays, but the Bactigen assay performed best, detecting as little as 1 ng of GBS group-specific antigen per ml in urine and as few as 10(5) CFU of GBS type III organisms per ml in urine, serum, and cerebrospinal fluid.
Publisher
American Society for Microbiology
Reference14 articles.
1. The emergence of group B streptococci in infections of the newborn infant. Annu;Anthony B. F.;Rev. Med.,1977
2. Commercial latex agglutination for detection of group B streptococcal antigen in body fluids;Baker C. J.;J. Pediatr.,1983
3. The poor sensitivity of urine latex agglutination testing in neonates with group B streptococcal bacteremia;Becker J. A.;Pediatr. Res.,1991
4. Polyclonal anti-group B Streptococcus latex antigen detection test;Bleeker D. L.;Pediatr. Infect. Dis. J.,1989
5. Soluble group- and type-specific antigens from type III group B Streptococcus;Carey R. B.;Infect. Immun.,1980
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