Detection of Group A Streptococcus in Pharyngeal Swab Specimens by Use of the AmpliVue GAS Isothermal Helicase-Dependent Amplification Assay-Reference-Cited by-同舟云学术

Detection of Group A Streptococcus in Pharyngeal Swab Specimens by Use of the AmpliVue GAS Isothermal Helicase-Dependent Amplification Assay

Published:2015-05-13 Issue:7 Volume:53 Page:2365-2367
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J. Clin. Microbiol.

Author:

Faron Matthew L.,Ledeboer Nathan A.,Granato Paul,Daly Judy A.,Pierce Kristina,Pancholi Preeti,Uphoff Timothy S.,Buchan Blake W.^ORCID

Abstract

We evaluated the clinical performance (sensitivity and specificity) of the AmpliVue group AStreptococcus(GAS) isothermal helicase-dependent amplification assay using 1,192 pharyngeal swab specimens. AmpliVue GAS assay results were compared to the results of routine throat cultures on selective streptococcal blood agar plates. The sensitivity and specificity of the AmpliVue GAS assay were 98.3% (95% confidence interval [CI], 95 to 100%) and 93.2% (95% CI, 91 to 95%), respectively.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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