Exploration of the Pharmacodynamics for Pseudomonas aeruginosa Biofilm Eradication by Tobramycin

Author:

Sindeldecker Devin12ORCID,Prakash Shaurya34,Stoodley Paul156

Affiliation:

1. Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA

2. Biomedical Sciences Graduate Program, The Ohio State University, Columbus, Ohio, USA

3. Department of Mechanical & Aerospace Engineering, The Ohio State University, Columbus, Ohio, USA

4. Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA

5. Department of Orthopaedics, The Ohio State University, Columbus, Ohio, USA

6. National Center for Advanced Tribology at Southampton (nCATS), Mechanical Engineering, University of Southampton, Southampton, United Kindgom

Abstract

Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen which is involved in numerous infections. It is of growing concern within the field of antibiotic resistance and tolerance and often exhibits multidrug resistance.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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