Adjuvant β-Lactam Therapy Combined with Vancomycin or Daptomycin for Methicillin-Resistant Staphylococcus aureus Bacteremia: a Systematic Review and Meta-analysis-Reference-Cited by-同舟云学术

Adjuvant β-Lactam Therapy Combined with Vancomycin or Daptomycin for Methicillin-Resistant Staphylococcus aureus Bacteremia: a Systematic Review and Meta-analysis

Published:2020-10-20 Issue:11 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Wang Chunjiang¹,Ye Chao²^ORCID,Liao Linglong³,Wang Zhaohui²,Hu Ying²,Deng Chao⁴,Liu Liang⁵

Affiliation:

1. Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China

2. Department of Pharmacy, People’s Hospital of Ningxiang City, Hunan University of Chinese Medicine, Changsha, Hunan, China

3. Gastroenterology, Zengcheng District People’s Hospital of Guangzhou, Guangzhou, Guangdong, China

4. Department of Pharmacy, Jingshan Union Hospital of Huazhong University of Science and Technology, Jingshan, Hubei, China

5. Neurosurgery, People’s Hospital of Ningxiang City, Hunan University of Chinese Medicine, Changsha, Hunan, China

Abstract

Infections due to methicillin-resistant Staphylococcus aureus bacteremia (MRSAB) seriously threaten public health due to poor outcomes and high mortality. The objective of this study is to perform a systematic review and meta-analysis of the current evidence on adjuvant β-lactam (BL) therapy combined with vancomycin (VAN) or daptomycin (DAP) for MRSAB. PubMed, Embase, and Cochrane Library were systematically searched for publications reporting clinical outcomes of BLs+VAN or BLs+DAP for adult patients with MRSAB through 5 April 2020.

Funder

Natural Science Foudation of Hunan Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01377-20

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