Four-Parameter FluoroSpot Assay Reveals That the Varicella Zoster Virus Elicits a Robust Memory T Cell IL-10 Response throughout Childhood-Reference-Cited by-同舟云学术

Four-Parameter FluoroSpot Assay Reveals That the Varicella Zoster Virus Elicits a Robust Memory T Cell IL-10 Response throughout Childhood

Published:2022-11-23 Issue:22 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Nilsson Anna¹^ORCID,Höbinger Anna¹,Jahnmatz Peter²³,Tiselius Eva¹,Laestadius Åsa⁴,Melén Erik⁵,Björkander Sophia⁵,Saghafian-Hedengren Shanie¹

Affiliation:

1. Department of Women’s and Children’s Health, Division of Paediatric Oncology and Paediatric Surgery, Karolinska Institutet, Stockholm, Sweden

2. Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet and Center for Molecular Medicine, Stockholm, Sweden

3. Mabtech AB, Nacka Strand, Sweden

4. Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden

5. Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden

Abstract

Infection with herpesviruses accounts for 35 to 40 billion human cases worldwide. Despite this, little is known about how herpesviruses shape the immune system in the asymptomatic carrier.

Funder

Karolinska Institutet

H.K.H. Kronprinsessan Lovisas Förening för Barnasjukvård

Sällskapet Barnavård

Magnus Bergvalls Stiftelse

Stiftelsen Lars Hiertas Minne

Stiftelsen Frimurare Barnhuset i Stockholm

Region Stockholm through ALF grant

Region Stockholm through ALF

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01310-22

Reference39 articles.

1. Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

2. Effects of nongenetic factors on immune cell dynamics in early childhood: The Generation R Study

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4. Immune system development varies according to age, location, and anemia in African children

5. Shaping Variation in the Human Immune System

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