Author:
Biggar W D,Bohn D J,Kent G,Barker C,Hamilton G
Abstract
The effect of hypothermia on pig leukocyte migration in vitro and in vivo was studied. Neutrophil chemotaxis in vitro under agarose was significantly impaired at 29 degrees C (2.7 +/- 0.6 [mean +/- standard error]; 37 degrees C, 7.1 +/- 1.1). Leukocytes isolated from hypothermic pigs and tested at 37 degrees C migrated normally (7.8 +/- 0.6). Neutrophil and monocyte migration in vivo was markedly reduced at 29 degrees C. Reduced inflammatory responses may contribute to increased infections during hypothermia.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference18 articles.
1. Neutrophil circulation and release from bone marrow during hypothermia;Biggar W. D.;Infect. Immun.,1983
2. Prolonged hypothermia in experimental pneumococcal peritonitis;Elseman B.;J. Clin. Invest.,1956
3. Outcome in severe Reye's syndrome with early phenobarbital coma and hypothermia;Frewen R. C.;J. Pediatr.,1982
4. The influence of hypothermia on experimental bacteremia in dogs;Gowen G. E.;Surgery,1961
5. Changes in blood cellular elements in dogs during hypothermia;Helmsworth J. A.;Surgery,1955
Cited by
64 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献