Value of the Concomitant Use of Complement Fixation and Immunodiffusion Tests in the Diagnosis of Coccidioidomycosis-Reference-Cited by-同舟云学术

Value of the Concomitant Use of Complement Fixation and Immunodiffusion Tests in the Diagnosis of Coccidioidomycosis

Published:1974-10 Issue:4 Volume:28 Page:641-643
ISSN:0003-6919
Container-title:Applied Microbiology
language:en
Short-container-title:Appl Microbiol

Author:

Kaufman Leo¹,Clark Maxine J.¹

Affiliation:

1. Center for Desease Control, Health Services and Mental Health Administration, Atlanta, Georgia 30333

Abstract

Complement fixation titers of 1:2 and 1:4 with coccidioidin are not always of diagnostic significance. The concurrent use of the complement fixation and immunodiffusion tests is an effective means for specific serologic diagnosis of coccidioidomycosis in patients with low levels of complement-fixing antibodies. In routine testing, it is recommended that only sera that are negative for complement-fixing antibodies at 1:8 but positive in the immunodiffusion test with coccidioidin be selected for titration at the 1:2 and 1:4 levels.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://journals.asm.org/doi/pdf/10.1128/am.28.4.641-643.1974

Reference9 articles.

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3. Immunodiffusion as a screening test for coccidioidomycosis serology;Huppert M.;Sabouraudia,1963

4. The use of immunodiffusion tests in coccidioidomycosis;Huppert M.;Amer. J. Clin. Pathol.,1965

5. Comparison of methods for coccidioidomycosis complement fixation;Huppert M.;Appl. Microbiol.,1970

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