Effect of p H on In Vitro Phagocytosis of Streptococcus pyogenes

Author:

Beck A.1,Bergner-Rabinowitz Sonia1,Ofek I.1

Affiliation:

1. Government Central Laboratories, Ministry of Health, Jerusalem, Israel

Abstract

Phagocytosis experiments were performed with mouse peritoneal leucocytes (MPL). The natural p H of the mouse peritoneal cavity was found to be between 6.1 and 6.3. The phagocytic and intracellular killing activities of MPL by p H variations was studied. It was observed that the optimal ingestion and intracellular killing of bacteria is at the natural p H of the peritoneal cavity.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference7 articles.

1. Identifications of type specific streptococci antibodies by in vitro phagocytosis;Bergner-Rabinowitz Sonia;Israel J. Med. Sci.,1969

2. Effect of partially purified streptococcal M protein on the in vitro phagocytosis of Streptococcus pyogenes;Dominique G. J.;J. Bacteriol.,1965

3. Methods for the study of human leucocytes;Martin S. P.;Med. Res.,1958

4. Opsonic capacity of type specific streptococcal antibodies;Ofek I.;Israel J. Med. Sci.,1969

5. Adherence and phagocytosis of Erythrocytes by in vitro cultured macrophages;Schwartz Jeanna;RES J. Reticuloendothe. Soc.,1967

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