Exogenous thymidine is preferentially incorporated into human cytomegalovirus DNA in infected human fibroblasts-Reference-Cited by-同舟云学术

Exogenous thymidine is preferentially incorporated into human cytomegalovirus DNA in infected human fibroblasts

Published:1996-09 Issue:9 Volume:70 Page:6402-6404
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Morin J¹,Johann S¹,O'Hara B¹,Gluzman Y¹

Affiliation:

1. Infectious Disease Section, Wyeth-Ayerst Research, Pearl River, New York 10965, USA.

Abstract

The effect of human cytomegalovirus infection on cellular DNA synthesis in human fibroblasts was measured by fluorometry and by incorporation of radiolabeled thymidine. The results show that although HCMV infection stimulates cellular DNA synthesis in both quiescent and serum-stimulated cells, radiolabeled thymidine is almost exclusively incorporated into viral DNA.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.70.9.6402-6404.1996

Reference18 articles.

1. Cell-activation responses to cytomegalovirus infection: relationship to the phasing of CMV replication and to the induction of cellular damage;Albrecht T.;Subcell. Biochem.,1989

2. Taxol inhibits stimulation of cell DNA synthesis by human cytomegalovirus;Ball R. L.;Exp. Cell Res.,1990

3. A human cytomegalovirus mutant resistant to the nucleoside analog 9-{[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl}guanine (BW B759U) induces reduced levels of BW B759U triphosphate;Biron K. K.;Proc. Natl. Acad. Sci. USA,1986

4. The kinetics of serum-induced initiation of DNA synthesis in BHK 21/C13 cells, and the influence of exogenous adenosine;Brooks R. F.;J. Cell. Physiol.,1975

5. Correlation between stimulation of host cell DNA synthesis by human cytomegalovirus and lack of expression of a subset of early virus genes;DeMarchi J. M.;Virology,1983

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Cellular Protein MCM3AP Is Required for Inhibition of Cellular DNA Synthesis by the IE86 Protein of Human Cytomegalovirus;PLoS ONE;2012-10-19

2. Functional Roles of the Human Cytomegalovirus Essential IE86 Protein;Current Topics in Microbiology and Immunology;2008

3. Host DNA Replication Is Induced by Geminivirus Infection of Differentiated Plant Cells;The Plant Cell;2002-11-20

4. The Human Cytomegalovirus IE86 Protein Can Block Cell Cycle Progression after Inducing Transition into the S Phase of Permissive Cells;Journal of Virology;2000-08

5. Human cytomegalovirus mediates cell cycle progression through G1 into early S phase in terminally differentiated cells;Journal of General Virology;2000-06-01