Affiliation:
1. Section of Microbial Pathogenesis, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Ave., New Haven, Connecticut 06536
Abstract
ABSTRACT
Campylobacter jejuni
is a leading cause of food-borne illness in the United States. Despite significant recent advances, its mechanisms of pathogenesis are poorly understood. A unique feature of this pathogen is that, with some exceptions, it lacks homologs of known virulence factors from other pathogens. Through a genetic screen, we have identified a
C. jejuni
homolog of the VirK family of virulence factors, which is essential for antimicrobial peptide resistance and mouse virulence.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Cited by
19 articles.
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