Serologic type conversion of a herpes simplex virus type 1 (HSV-1) to an HSV-2 epitope caused by a single amino acid substitution in glycoprotein C-Reference-Cited by-同舟云学术

Serologic type conversion of a herpes simplex virus type 1 (HSV-1) to an HSV-2 epitope caused by a single amino acid substitution in glycoprotein C

Published:1990-08 Issue:8 Volume:64 Page:4033-4036
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Kimmel K A¹,Dolter K E¹,Toth G M¹,Levine M¹,Glorioso J C¹

Affiliation:

1. Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor 48109.

Abstract

A monoclonal antibody to herpes simplex virus type 2 glycoprotein C (gC-2) did not recognize wild-type herpes simplex virus type 1 gC (gC-1) but did recognize a mutant gC-1 molecule. This conversion from a type 1 to a type 2 epitope was shown to be due to a single amino acid substitution in gC-1.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.64.8.4033-4036.1990

Reference23 articles.

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