In Vitro Activity of Plazomicin against Gram-Negative and Gram-Positive Isolates Collected from U.S. Hospitals and Comparative Activities of Aminoglycosides against Carbapenem-Resistant Enterobacteriaceae and Isolates Carrying Carbapenemase Genes

Author:

Castanheira Mariana1,Davis Andrew P.1,Mendes Rodrigo E.1,Serio Alisa W.2,Krause Kevin M.2,Flamm Robert K.1

Affiliation:

1. JMI Laboratories, North Liberty, Iowa, USA

2. Achaogen, South San Francisco, California, USA

Abstract

Plazomicin and comparator agents were tested by using the CLSI reference broth microdilution method against 4,825 clinical isolates collected during 2014 and 2015 in 70 U.S. hospitals as part of the ALERT (Antimicrobial Longitudinal Evaluation and Resistance Trends) program.

Funder

Achaogen

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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