Genome-Wide Identification of Novel sRNAs in Streptococcus mutans-Reference-Cited by-同舟云学术

Genome-Wide Identification of Novel sRNAs in Streptococcus mutans

Published:2022-04-19 Issue:4 Volume:204 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Krieger Madeline C.¹²,Merritt Justin²^ORCID,Raghavan Rahul¹³^ORCID

Affiliation:

1. Department of Biology, Portland State University, Portland, Oregon, USA

2. Department of Restorative Dentistry, School of Dentistry, Oregon Health and Science University, Portland, Oregon, USA

3. Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio, San Antonio, Texas, USA

Abstract

Small RNAs (sRNAs) are important gene regulators in bacteria, but the identities and functions of sRNAs in Streptococcus mutans , the principal bacterium involved in the formation of dental caries, are unknown. In this study, we identified 15 putative sRNAs in S. mutans and show that they respond to four common stress-inducing conditions present in human mouth: sugar-phosphate stress, hydrogen peroxide exposure, high temperature, and low pH.

Funder

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00577-21

Reference69 articles.

1. Streptococcus mutans, Caries and Simulation Models

2. Virulence Factors of Streptococcus mutans and Dental Caries Prevention

3. Role of Streptococcus mutans in human dental decay