The Effect of Nitric Oxide on Bacteria

Author:

Shank J. L.1,Silliker J. H.1,Harper R. H.1

Affiliation:

1. Research Laboratories, Swift and Company, Chicago, Illinois

Abstract

Nitric oxide, as well as several other oxides of nitrogen, were assayed for their antibacterial action. It is shown that nitric oxide has virtually no effect on bacteria, whereas both NaNO 3 and NaNO 2 appear to have either neutral or stimulatory effects. It is suggested that the formation of nitrous acid is mainly responsible for the quantitative as well as the qualitative changes that occur in the bacterial flora of cured meat. A pH-dependent “nitrite cycle” is presented to account for the production of nitrous acid in cured meat systems.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference29 articles.

1. AOAC. 1960. Official and tentative methods of analysis of the Association of Official Agricultural Chemists. 9th ed. George Banta Publishing Co. Menasha Wisc.

2. Microorganisms associated with development of slimiie on eviscerated cut-up poultry;AYRES J. C.;Food Technol.,1954

3. BREED R. S. E. G. D. MURRAY AND N. R. SMITH. 1957. Bergey's manual of determinative bacteriology. 7th ed. The Williams & Wilkins Co. Baltimore. 1094 p.

4. Preservative effect of various concentrations of curing salts in comminuted pork;BULMAN C.;Food Technol.,1952

5. Factors affecting the bacteriostatic action of sodium nitrite;CASTELLANI A. G;Appl. Microbiol.,1955

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