Emergence of Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Coharboring a bla NDM-1 -Carrying Virulent Plasmid and a bla KPC-2 -Carrying Plasmid in an Egyptian Hospital-Reference-Cited by-同舟云学术

Emergence of Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Coharboring a bla NDM-1 -Carrying Virulent Plasmid and a bla KPC-2 -Carrying Plasmid in an Egyptian Hospital

Published:2021-05-19 Issue: Volume: Page:
ISSN:2379-5042
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language:en
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Author:

Ahmed Mohamed Abd El-Gawad El-Sayed¹²³⁴^ORCID,Yang Yanxian²³,Yang Yongqiang²³⁵,Yan Bin²³⁶,Chen Guanping⁷,Hassan Reem Mostafa⁸,Zhong Lan-Lan²³,Chen Yuan⁷,Roberts Adam P.⁹¹⁰^ORCID,Wu Yiping²³,He Ruowen²³,Liang Xiaoxue¹¹,Qin Mingyang¹,Dai Min¹¹,Zhang Liyan¹²,Li Hongyu¹³,Yang Fan¹,Xu Lingqing¹⁴,Tian Guo-Bao²³¹⁵^ORCID

Affiliation:

1. Department of Microbiology, School of Basic Medical Science, Xinxiang Medical University, Xinxiang, China

2. Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

3. Key Laboratory of Tropical Diseases Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China

4. Department of Microbiology and Immunology, Faculty of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Egypt

5. School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Guangzhou, China

6. Department of Neonatal Surgery, Guangzhou Women and Children's Medical Center, Guangzhou, China

7. Sun Yat-Sen University School of Medicine, Guangzhou, China

8. Department of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt

9. Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

10. Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

11. School of Laboratory Medicine, Chengdu Medical College, Chengdu, China

12. Department of Clinical Laboratory, Guangdong Provincial People’s Hospital/Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China

13. Department of Clinical Laboratory, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China

14. Department of Clinical Laboratory, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, China

15. School of Medicine, Xizang Minzu University, Xianyang, Shaanxi, China

Abstract

CRKP has been registered in the critical priority tier by the World Health Organization and has become a significant menace to public health. The emergence of CR-HvKP is of great concern in terms of both disease and treatment.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00088-21

Reference21 articles.

1. Carbapenem-resistant Gram-negative bacteria associated with catheter-related bloodstream infections in three intensive care units in Egypt

2. Carbapenem-resistant Klebsiella pneumoniae isolates from Egypt containing bla NDM-1 on IncR plasmids and its association with rmtF

3. Carbapenemase-producing Klebsiella pneumoniae in broiler poultry farming in Egypt