Distribution of Antimicrobial Resistance and Virulence Genes within the Prophage-Associated Regions in Nosocomial Pathogens-Reference-Cited by-同舟云学术

Distribution of Antimicrobial Resistance and Virulence Genes within the Prophage-Associated Regions in Nosocomial Pathogens

Published:2021-08-25 Issue:4 Volume:6 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Kondo Kohei¹^ORCID,Kawano Mitsuoki²^ORCID,Sugai Motoyuki¹^ORCID

Affiliation:

1. Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Higashi Murayama, Tokyo, Japan

2. Department of Human Nutrition, Faculty of Contemporary Life Science, Chugokugakuen University, Kita-ku, Okayama, Japan

Abstract

Although we believe phages play an important role in horizontal gene transfer in exchanging genetic material, we do not know the distribution of the antimicrobial resistance (AMR) and/or virulence factor (VF) genes in prophages. We collected different prophage elements from the complete genome sequences of seven species— Enterococcus faecium , Staphylococcus aureus , Klebsiella pneumoniae , Acinetobacter baumannii , Pseudomonas aeruginosa , Enterobacter cloacae , and Escherichia coli —and characterized the distribution of antimicrobial resistance and virulence genes encoded in the prophage region.

Funder

MEXT | Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00452-21

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