Options for Synthetic DNA Order Screening, Revisited-Reference-Cited by-同舟云学术

Options for Synthetic DNA Order Screening, Revisited

Published:2017-08-30 Issue:4 Volume:2 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

DiEuliis Diane¹,Carter Sarah R.²,Gronvall Gigi Kwik³^ORCID

Affiliation:

1. Center for the Study of Weapons of Mass Destruction, National Defense University, U.S. Department of Defense, Washington, DC, USA

2. Science Policy Consulting LLC, Arlington, Virginia, USA

3. Johns Hopkins Center for Health Security, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

Abstract

Gene synthesis providers affiliated with the International Gene Synthesis Consortium (IGSC) voluntarily screen double-stranded DNA (dsDNA) synthesis orders over 200 bp to check for matches to regulated pathogens and to screen customers. Questions have been raised, however, about the continuing feasibility and effectiveness of screening.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00319-17

Reference8 articles.

1. How Canadian researchers reconstituted an extinct poxvirus for $100,000 using mail-order DNA

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3. Federal Select Agent Program . 2017. Select agents and toxins list. http://www.selectagents.gov/SelectAgentsandToxinsList.html . Division of Select Agents and Toxins, Centers for Disease Control and Prevention, Atlanta, GA,

4. The Australia Group . 2017. Australia Group common control lists. http://www.australiagroup.net/en/controllists.html

5. US Department of Commerce . 2013. Biological agents and genetic elements (AG list plus Select Agents), US Commerce Control List, section 1C351-4. US Department of Commerce, Washington, DC.

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