Helicobacter pylori and Epstein-Barr Virus Coinfection Stimulates Aggressiveness in Gastric Cancer through the Regulation of Gankyrin

Author:

Kashyap Dharmendra1,Baral Budhadev1,Jakhmola Shweta1,Singh Anil Kumar2,Jha Hem Chandra1ORCID

Affiliation:

1. Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, Indore, India

2. Biological Science and Technology Division, CSIR-Northeast Institute of Science and Technology, Jorhat, India

Abstract

In the present study, we evaluated the synergistic effects of EBV and H. pylori infection on gastric epithelial cells in various coinfection models. These coinfection models were among the first to depict the exposures of gastric epithelial cells to EBV followed by H. pylori ; however, coinfection models exist that narrated the scenario upon exposure to H. pylori followed by that to EBV.

Funder

DST | Science and Engineering Research Board

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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