Prevention of Assay Interference in Infectious-Disease Serology Tests Done on the Liaison Platform-Reference-Cited by-同舟云学术

Prevention of Assay Interference in Infectious-Disease Serology Tests Done on the Liaison Platform

Published:2008-05 Issue:5 Volume:15 Page:891-892
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Berth Mario¹,Bosmans Eugene¹

Affiliation:

1. Algemeen Medisch Laboratorium, Immunology Department, Desguinlei 88, 2018 Antwerpen, Belgium

Abstract

ABSTRACT Immunoassay interference causing unexpected reactive results in magnetic-microparticle-based assays was detected. A systematic evaluation of Liaison Epstein-Barr virus immunoglobulin M showed that 5% of the positive results (0.4% of tested samples) could be explained by such interference. Adding chemical blocking reagents (polyvinylpyrrolidone and polyvinyl alcohol) to the assay buffers partially prevented this phenomenon.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00012-08

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