Use of Protein-Specific Monoclonal Antibody-Based Latex Agglutination for Rapid Diagnosis of Burkholderia pseudomallei Infection in Patients with Community-Acquired Septicemia-Reference-Cited by-同舟云学术

Use of Protein-Specific Monoclonal Antibody-Based Latex Agglutination for Rapid Diagnosis of Burkholderia pseudomallei Infection in Patients with Community-Acquired Septicemia

Published:2007-06 Issue:6 Volume:14 Page:811-812
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Ekpo Pattama¹²³,Rungpanich Utane¹²³,Pongsunk Supinya¹²³,Naigowit Pimjai¹²³,Petkanchanapong Vimon¹²³

Affiliation:

1. Department of Immunology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok

2. Department of Microbiology, Faculty of Medicine, Srinakarinwirot University, Bangkok

3. National Institute of Health, Department of Medical Services, Ministry of Public Health, Nonthaburi, Thailand

Abstract

ABSTRACT A latex agglutination test employing monoclonal antibody specific to a 30-kDa protein of Burkholderia pseudomallei was used to detect the organisms in blood culture specimens from 1,139 patients with community-acquired septicemia. The sensitivity, specificity, and positive and negative predictive values of the test were 96.75%, 99.61%, 96.75%, and 99.61%, respectively.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00011-07

Reference20 articles.

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4. Melioidosis: the tip of the iceberg?

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