Laboratory Evolution and Reverse Engineering of Clostridium thermocellum for Growth on Glucose and Fructose

Author:

Yayo Johannes1,Kuil Teun1,Olson Daniel G.23,Lynd Lee R.23,Holwerda Evert K.23ORCID,van Maris Antonius J. A.1ORCID

Affiliation:

1. Department of Industrial Biotechnology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, Sweden

2. Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA

3. The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

Abstract

C. thermocellum is an important candidate for sustainable and cost-effective production of bioethanol through consolidated bioprocessing. In addition to unsurpassed cellulose deconstruction, industrial application and fundamental studies would benefit from improvement of glucose and fructose consumption.

Funder

Formas, Sweden

BioEnergy Science Center

Center for Bioenergy Innovation

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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