Role of Signal-to-Cutoff Ratios in Hepatitis C Virus Antibody Detection-Reference-Cited by-同舟云学术

Role of Signal-to-Cutoff Ratios in Hepatitis C Virus Antibody Detection

Published:2012-06-13 Issue:8 Volume:19 Page:1329-1331
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin. Vaccine Immunol.

Author:

Moretti Marco,Pieretti Barbara,Masucci Annamaria,Sisti Davide,Rocchi Marco,Delprete Ernesto

Abstract

ABSTRACTWe reviewed results from 12,800 samples tested for hepatitis C virus (HCV) antibody detection in our laboratory by screening (Ortho chemiluminescence immunoassay [CIA]) and supplemental tests (Chiron recombinant immunoblot assay [RIBA]). We found that a signal-to-cutoff (S/Co) ratio of 10.3 was, in our setting, the most efficient cutoff point to improve the diagnostic algorithm of HCV infection.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

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