PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion
Author:
Affiliation:
1. Laboratory of Viral Immunopathology, Department of Infectious Diseases and Hepatology, Azienda Ospedaliera di Parma, Parma, Italy
2. Unità Operativa Malattie Infettive, Azienda Ospedaliera S. Maria Nuova di Reggio Emilia, Reggio Emilia, Italy
Abstract
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Link
https://journals.asm.org/doi/pdf/10.1128/JVI.01177-06
Reference17 articles.
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2. Expression of the Interleukin-7 Receptor Alpha Chain (CD127) on Virus-Specific CD8 + T Cells Identifies Functionally and Phenotypically Defined Memory T Cells during Acute Resolving Hepatitis B Virus Infection
3. Brown, J. A., D. M. Dorfman, F. R. Ma, E. L. Sullivan, O. Munoz, C. R. Wood, E. A. Greenfield, and G. J. Freeman. 2003. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J. Immunol.170:1257-1266.
4. Cai, G., A. Karni, E. M. Oliveira, H. L. Weiner, D. A. Hafler, and G. J. Freeman. 2004. PD-1 ligands, negative regulators for activation of naive, memory, and recently activated human CD4+ T cells. Cell Immunol.230:89-98.
5. Fuller, M. J., D. A. Hildeman, S. Sabbaj, D. E. Gaddis, T. E. Tebo, L. Shang, P. A. Goepfert, and A. J. Zajac. 2005. Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help. J. Immunol.174:5926-5930.
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