Orsay Virus Infection of Caenorhabditis elegans Is Modulated by Zinc and Dependent on Lipids-Reference-Cited by-同舟云学术

Orsay Virus Infection of Caenorhabditis elegans Is Modulated by Zinc and Dependent on Lipids

Published:2022-11-23 Issue:22 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Casorla-Perez Luis Alberto¹^ORCID,Guennoun Ranya¹,Cubillas Ciro¹,Peng Bo¹,Kornfeld Kerry²,Wang David¹³^ORCID

Affiliation:

1. Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA

2. Developmental Biology, School of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA

3. Department Pathology & Immunology, Washington University in St. Louis, St. Louis, Missouri, USA

Abstract

Orsay virus is the only known natural virus pathogen of Caenorhabditis elegans , which shares many evolutionarily conserved pathways with humans. We leveraged the powerful genetic tractability of C. elegans to characterize a novel interaction between zinc, lipids, and virus infection.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01211-22

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