Affiliation:
1. Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong
2. City University of Hong Kong Shenzhen Research Institute, Shenzhen, China
Abstract
A multidrug-resistant
Vibrio alginolyticus
isolate recovered from a shrimp sample with reduced carbapenem susceptibility produced a novel metallo-β-lactamase (MBL), VAM-1. That carbapenemase shared 67% to 70% amino acid identity with several VMB family subclass B1 MBLs, which were recently reported among some marine bacteria including
Vibrio
,
Glaciecola
, and
Thalassomonas
. The
bla
VAM-1
gene was located in a novel conjugative plasmid, namely, pC1579, and multiple copies of
bla
VAM-1
via an unusual mechanism of gene amplification were detected in pC1579.
Funder
National Key R&D Program of China
Basic Research Fund of Shenzhen
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
10 articles.
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