Affiliation:
1. Division of Clinical Microbiology, City Hospital Center at Elmhurst, New York 11373, USA.
Abstract
The CAPTIA Syphilis G enzyme-linked immunosorbent assay compared favorably with the rapid plasma reagin test when used to screen for syphilis in a low-risk population. The sensitivity and specificity of the CAPTIA Syphilis G test were 100 and 97.8%, respectively, for 646 routine specimens and 100 and 99.2%, respectively, for 265 specimens from obstetrics patients. Overall, for 911 specimens, the CAPTIA Syphilis G test showed a sensitivity of 100%, a specificity of 98.2%, and positive and negative predictive values of 78.9 and 100%, respectively. For the same population, the rapid plasma reagin test showed a sensitivity and a specificity of 96.4 and 97.5%, respectively, and positive and negative predictive values of 72 and 99.8%, respectively.
Publisher
American Society for Microbiology
Reference20 articles.
1. False-negative syphilis screening: the prozone phenomenon, nonimmune hydrops, and diagnosis of syphilis during pregnancy;Berkowitz K.;Am. J. Obstet. Gynecol.,1990
2. Evaluation of a solid-phase enzyme immunoassay in the diagnosis of syphilis;Borobio N. V.;Eur. J. Sex. Transm. Dis.,1985
3. Progress toward achieving the 1990 objectives for the nation for sexually transmitted diseases;Centers for Disease Control and Prevention.;Morbid. Mortal. Weekly Rep.,1990
4. Treponemal antibody-absorbent enzyme immunoassay for syphilis;Chen J. T.;J. Clin. Microbiol.,1986
5. Four-step enzyme-linked immunosorbent assay for detection of Treponema pallidum antibody;Farshy C. E.;J. Clin. Microbiol.,1985
Cited by
22 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献