The major capsid protein VP2 of minute virus of mice (MVM) can form particles which bind to the 3'-terminal hairpin of MVM replicative-form DNA and package single-stranded viral progeny DNA-Reference-Cited by-同舟云学术

The major capsid protein VP2 of minute virus of mice (MVM) can form particles which bind to the 3'-terminal hairpin of MVM replicative-form DNA and package single-stranded viral progeny DNA

Published:1993-09 Issue:9 Volume:67 Page:5660-5663
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Willwand K¹,Hirt B¹

Affiliation:

1. Swiss Institute for Experimental Cancer Research, Epalinges.

Abstract

The capsids of minute virus of mice (MVM) consist of two closely related proteins, VP1 and VP2. We inactivated the VP1 gene in an infectious clone of MVM DNA by frameshift mutation. After transfection of mutated DNA, capsids consisting of VP2 only were made. They can package negative-strand DNA, and they specifically bind MVM 3'-terminal hairpin DNA.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.67.9.5660-5663.1993

Reference19 articles.

1. Characterization of the cell-type-specific determinant in the genome of minute virus of mice;Antonietti J.;J. Virol.,1988

2. DNA sequence of a Iymphotropic variant of minute virus of mice, MVM(i), and comparison with the DNA sequence of the fibrotropic prototype strain;Astell C. R.;J. Virol.,1986

3. Structure of the 3'-hairpin termini of four rodent parvovirus genomes: nucleotide sequence homology at origins of DNA replication;Astell C. R.;Cell,1979

4. DNA of minute virus of mice: self-priming, nonpermuted, single-stranded genome with a 5'-terminal hairpin duplex;Bourguignon G. J.;J. Virol.,1976

5. The autonomously replicating parvoviruses of vertebrates;Cotmore S. F.;Adv. Virus Res.,1987

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