Engineering the Soil Bacterium Pseudomonas putida for Arsenic Methylation

Author:

Chen Jian12,Qin Jie1,Zhu Yong-Guan23,de Lorenzo V�ctor4,Rosen Barry P.1

Affiliation:

1. Department of Cellular Biology and Pharmacology, Florida International University, Herbert Wertheim College of Medicine, Miami, Florida, USA

2. State Key Lab of Regional and Urban Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China

3. Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, People's Republic of China

4. Centro Nacional de Biotecnolog�a-CSIC, Campus UAM-Cantoblanco, Madrid, Spain

Abstract

Accumulation of arsenic has potential health risks through consumption of food. Here, we inserted the arsenite [As(III)] S -adenosylmethionine methyltransferase (ArsM) gene into the chromosome of Pseudomonas putida KT2440. Recombinant bacteria methylate inorganic arsenic into less toxic organoarsenicals. This has the potential for bioremediation of environmental arsenic and reducing arsenic contamination in food.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Reference20 articles.

1. Arsenic toxicity, mutagenesis, and carcinogenesis—a health risk assessment and management approach;Tchounwou PB;Mol. Cell. Biochem.,2004

2. Health effects and risk assessment of arsenic;Abernathy CO;J. Nutr.,2003

3. Carcinogenic and systemic health effects associated with arsenic exposure—a critical review;Tchounwou PB;Toxicol. Pathol.,2003

4. Market basket survey shows elevated levels of As in South Central U.S. processed rice compared to California: consequences for human dietary exposure;Williams PN;Environ. Sci. Technol.,2007

5. Biotransformation of arsenic by a Yellowstone thermoacidophilic eukaryotic alga;Qin J;Proc. Natl. Acad. Sci. U. S. A.,2009

Cited by 76 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3