Antifungal macrodiolide from Streptomyces sp-Reference-Cited by-同舟云学术

Antifungal macrodiolide from Streptomyces sp

Published:1986-09 Issue:3 Volume:30 Page:458-464
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Jois H R,Sarkar A,Gurusiddaiah S

Abstract

Aerobic fermentation cultures of Streptomyces sp. produced an antifungal macrodiolide. This new antibiotic consists of two units of homononactic acid linked to form a cyclic diester. An unknown polypeptide was also isolated in trace quantities. The antibiotic with polypeptide complex showed high levels of antifungal activity compared with that of the macrodiolide alone. The macrodiolide also showed a stimulatory effect on some species of fungi. The production, purification, and characterization of these compounds are reported.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.30.3.458

Reference18 articles.

1. Metabolic products of actinomycetes. 35. Structures of monactin, dinactin and trinactin;Beck J.;Helv. Chim. Acta,1962

2. Buchanan R. E. and N. E. Gibbons (ed.). 1974. Bergey's manual of determinative bacteriology 8th ed. The Williams & Wilkins Co. Baltimore.

3. Pantomycin: a new antimicrobial antibiotic;Gurusiddaiah S.;Mycologia,1979

4. Two antibiotics identical with nonactin and valinomycin obtained from a Streptomyces tsusimaensis, n. sp;Haruo N.;J. Antibiot. Ser. A,1964

5. Stoffwechselproduckte von Mikroorganismen. 58. Mitteileing (1) neve makrotetrolide aus actinomyceten;Hutter H. R.;Helv. Chim. Acta,1967

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