Aminoglycoside-modifying enzymes in clinical isolates harboring extended-spectrum beta-lactamases

Author:

Fernandez-Rodriguez A1,Canton R1,Perez-Diaz J C1,Martinez-Beltran J1,Picazo J J1,Baquero F1

Affiliation:

1. Servicio de Microbiología, Hospital Clínico de San Carlos, Madrid, Spain.

Abstract

The aminoglycoside-modifying enzymes present in the first 120 clinical isolates harboring extended-spectrum beta-lactamases isolated in Spain were studied. Most of these isolates (84%) were gentamicin resistant. The enzymes most frequently associated and cotransferred with SHV-2 or TEM-type beta-lactamases were AAC(3)V, APH(3"), and APH(3')I.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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