Novel method for evaluating antiviral drugs against human cytomegalovirus in mice-Reference-Cited by-同舟云学术

Novel method for evaluating antiviral drugs against human cytomegalovirus in mice

Published:1992-01 Issue:1 Volume:36 Page:206-208
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Allen L B¹,Li S X¹,Arnett G¹,Toyer B¹,Shannon W M¹,Hollingshead M G¹

Affiliation:

1. Southern Research Institute, Birmingham, Alabama 35255.

Abstract

A virus-host cell system in which human cytomegalovirus-infected human cells are entrapped in agarose plugs has been developed. This model provides an inexpensive method for the in vivo evaluation (with outbred, immunocompetent mice) of antiviral drugs against human viruses such as cytomegalovirus that replicate primarily or only in human cells.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.36.1.206

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