Mechanism of Macrolide-Induced Inhibition of Pneumolysin Release Involves Impairment of Autolysin Release in Macrolide-Resistant Streptococcus pneumoniae-Reference-Cited by-同舟云学术

Mechanism of Macrolide-Induced Inhibition of Pneumolysin Release Involves Impairment of Autolysin Release in Macrolide-Resistant Streptococcus pneumoniae

Published:2018-11 Issue:11 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Domon Hisanori¹²^ORCID,Maekawa Tomoki¹²³,Yonezawa Daisuke¹²⁴,Nagai Kosuke¹,Oda Masataka⁵,Yanagihara Katsunori⁶,Terao Yutaka¹²

Affiliation:

1. Division of Microbiology and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

2. Research Center for Advanced Oral Science, Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan

3. Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

4. Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

5. Department of Microbiology and Infection Control Sciences, Kyoto Pharmaceutical University, Kyoto, Japan

6. Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

Abstract

Streptococcus pneumoniae is a leading cause of community-acquired pneumonia. Over the past 2 decades, macrolide resistance among S. pneumoniae organisms has been increasing steadily and has escalated at an alarming rate worldwide.

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00161-18

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