Disseminated Toxoplasmosis, Resulting from Infection of Allograft, after Orthotopic Liver Transplantation: Usefulness of Quantitative PCR-Reference-Cited by-同舟云学术

Disseminated Toxoplasmosis, Resulting from Infection of Allograft, after Orthotopic Liver Transplantation: Usefulness of Quantitative PCR

Published:2002-05 Issue:5 Volume:40 Page:1648-1650
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Botterel F.¹,Ichai P.²,Feray C.²,Bouree P.¹,Saliba F.²,Tur Raspa R.³,Samuel D.²,Romand S.¹⁴

Affiliation:

1. Service de Microbiologie, Departement de Parasitologie-Mycologie, Hopital de Bicetre, Faculté de Médecine Paris-Sud, 94275 Kremlin-Bicetre Cedex

2. Centre Hépatobiliaire, Paul Brousse Hospital, 94804 Villejuif

3. Liver Unit, Rabin Medical Center, Tel Aviv, Israel

4. Institut de Puericulture, F 75014 Paris, France

Abstract

ABSTRACT Disseminated toxoplasmosis is a life-threatening disease in liver transplant recipients that can result from an organ-transmitted infection. We report here a case of fatal disseminated toxoplasmosis after orthotopic liver transplantation from a seropositive donor (immunoglobulin G [IgG] + and IgM − ) in a patient who was nonimmune for toxoplasmosis prior to transplantation. Quantitative PCR analyses of various clinical specimens, including serum samples, appeared retrospectively to be a valuable diagnostic tool that might guide therapeutic attitudes.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.40.5.1648-1650.2002

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