Evaluation of the Vitek 2, Phoenix, and MicroScan for Antimicrobial Susceptibility Testing of Stenotrophomonas maltophilia

Author:

Khan Ayesha12ORCID,Arias Cesar A.1234,Abbott April5,Dien Bard Jennifer6ORCID,Bhatti Micah M.7,Humphries Romney M.8ORCID

Affiliation:

1. Center for Antimicrobial Resistance and Microbial Genomics, UTHealth, Houston, Texas, USA

2. Division of Infectious Diseases, McGovern Medical School, UTHealth, Houston, Texas, USA

3. Center for Infectious Diseases, University of Texas Health Science Center, School of Public Health, Houston, Texas, USA

4. Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, Bogotá, Colombia

5. Deaconess Health System, Indiana University Medical School, Evansville, Indiana, USA

6. Department of Pathology and Laboratory Medicine, Children’s Hospital of Los Angeles, Keck school of Medicine, University of Southern California, Los Angeles, California, USA

7. Department of Pathology and Laboratory Medicine, MD Anderson Cancer Center, Houston, Texas, USA

8. Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

Abstract

Stenotrophomonas maltophilia causes high-mortality infections in immunocompromised hosts with limited therapeutic options. Many U.S. laboratories rely on commercial automated antimicrobial susceptibility tests (cASTs) and use CLSI breakpoints (BPs) for S. maltophilia .

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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