5-Methyl-2-thiouridine in the tRNA of Candida tropicalis and its localization in lysine tRNA

Author:

Patwardhan S,Cherayil J D

Abstract

35S incorporation studies showed that Candida tropicalis tRNA contained two thionucleosides, one of which was identified as 5-methyl-2-thiouridine. The other thionucleoside was alkali labile, and it appeared to be an ester. Pulse-chase experiments suggested that the two thionucleosides were structurally related. 5-Methyl-2-thiouridine was present in one of the lysine tRNAs. This is the first report of the presence of this nucleoside in a yeast tRNA.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference18 articles.

1. Chromatography of sRNA on DEAE-cellulose and DEAE-Sephadex;Bock R. M.;Methods Enzymol.,1967

2. Thiobases in Escherichia coli transfer RNA;Carbon J.;Science,1968

3. Changes in 2-thiouridine derivatives in transfer RNA of Agrobacterium tumefaciens;Chackalaparampil I.;Biochem. Int.,1981

4. The nucleotide sequence of glutamate tRNA from rat liver;Chan J. C.;Nucleic Acids Res.,1982

5. Gauss D. H. and M. S. Sprinzl. 1983. Compilation of tRNA sequences. Nucleic Acids Res. 11:rl-r53.

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