Affiliation:
1. Venereal Disease Research Laboratory, Venereal Disease Branch, Communicable Disease Center, Public Health Service, Atlanta, Georgia
Abstract
Immunofluorescence was used as an aid in the antigenic grouping of 14 cultivable treponemes. Antisera were prepared versus each treponemal strain, and the antiglobulins were conjugated with fluorescein isothiocyanate. A common antigen-antibody system, detected in the strains studied, was removed by absorption of each conjugate with Reiter or
Borrelia vincentii
treponemes. Thus, five categories based on shared group-specific antigens were revealed. Serogroup I: Reiter, English Reiter, Kazan, Kazan numbers 2, 4, 5, and 8. Serogroup II: Nichols and Noguchi. Serogroup III: three oral treponemes, MRB, FM, and N-39. Serogroup IV:
B. vincentii
. Serogroup V:
Treponema zuelzerae
. The five serogroups apparently are related by an immunofluorescent common antigen.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference18 articles.
1. The role of the spirochaete in the Wassermann reaction;BECK A.;J. Hyg.,1939
2. Serological relationship between Treponema zuelzerae and the Reiter strain of Treponema pallidum. Antonie van Leeuwenhoek J;BRU JN, J;Microbiol. Serol.,1961
3. The demonstration of a common antigen in Reiter's treponeme and virulent Treponema pallidum;CANNEFAX G. R.;J. Immunol.,1959
4. Studies on the antigenic structure of T. pallidum. 4. Comparison between the cultivable strains of T. reiter and T. Kazan II, applying agar gel diffusion technique and cross absorption experiments;CHRISTIANSEN A. H.;Acta Pathol. Microbiol. Scand.,1964
5. Isolation and purification of the protein antigen of the Reiter treponeme;D'ALESSANDRO G.;Am. J. Syphilis. Gonorrhea Venereal Diseases,1953
Cited by
31 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Treponema;Bergey's Manual of Systematics of Archaea and Bacteria;2015-09-14
2. Phylum XV. Spirochaetes Garrity and Holt 2001;Bergey’s Manual® of Systematic Bacteriology;2010
3. Spirochaetes in oral infections;Dental Traumatology;1993-06
4. A common antigen of Treponema denticola and other Treponema species detected by monoclonal antibody;Oral Microbiology and Immunology;1989-06
5. Experimental Syphilis in Guinea Pig;CRC Critical Reviews in Microbiology;1989-01