Multidrug-Resistant Gram-Negative Bacteria in Burn Patients

Author:

Ruegsegger Laura1,Xiao Jamie1,Naziripour Arash1,Kanumuambidi Trey1,Brown Dylan1,Williams Felicia2,Marshall Steven H.3,Rudin Susan D.34,Yen Kelly5,Chu Tingyu5,Chen Liang5ORCID,Sozzi Emanuele6,Bartelt Luther1,Kreiswirth Barry5,Bonomo Robert A.3478ORCID,van Duin David1ORCID

Affiliation:

1. Division of Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina, USA

2. Department of Surgery, University of North Carolina, Chapel Hill, North Carolina, USA

3. Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA

4. Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

5. Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA

6. Department of Environmental Science and Engineering, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA

7. Departments of Pharmacology, Molecular Biology and Microbiology, Biochemistry, and Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

8. CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA

Abstract

Patients with burn injuries are at high risk for infectious complications, and infections are the most common cause of death after the first 72 h of hospitalization. Hospital-acquired infections caused by multidrug resistant (MDR) Gram-negative bacteria (GNB) in this population are concerning.

Funder

HHS | NIH | NIAID | Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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