Quantitative PCR (qPCR) Detection of Mucorales DNA in Bronchoalveolar Lavage Fluid To Diagnose Pulmonary Mucormycosis-Reference-Cited by-同舟云学术

Quantitative PCR (qPCR) Detection of Mucorales DNA in Bronchoalveolar Lavage Fluid To Diagnose Pulmonary Mucormycosis

Published:2018-08 Issue:8 Volume:56 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Scherer Emeline¹²,Iriart Xavier³⁴,Bellanger Anne Pauline¹²,Dupont Damien⁵⁶,Guitard Juliette⁷⁸,Gabriel Frederic⁹,Cassaing Sophie³¹⁰,Charpentier Eléna³⁴,Guenounou Sarah¹¹,Cornet Murielle¹²^ORCID,Botterel Françoise¹³,Rocchi Steffi¹²,Berceanu Ana¹⁴,Millon Laurence¹²

Affiliation:

1. Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire, Besançon, France

2. UMR ChronoEnvironnement CNRS 6249, Université Bourgogne Franche-Comté, Besançon, France

3. Service de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Toulouse, Toulouse, France

4. CPTP, Université de Toulouse, CNRS, Inserm, UPS, Toulouse, France

5. Hospices Civils de Lyon, Institut des Agents Infectieux, Parasitologie Mycologie, Lyon, France

6. Integrative Physiology of the Brain Arousal Systems, Centre de Recherche en Neurosciences de Lyon, INSERM U1028-CNRS UMR 5292, Université Claude Bernard Lyon 1, Lyon, France

7. AP-HP, Hôpital Saint-Antoine, Service de Parasitologie-Mycologie, Paris, France

8. Sorbonne Universités, UPMC Université Paris 06, INSERM, Centre de Recherche Saint-Antoine (CRSA), Paris, France

9. Laboratoire de Parasitologie Mycologie, Centre Hospitalier Universitaire Pellegrin, Bordeaux, France

10. Equipe RMN2i, UMR 152 PharmaDEV, IRD, Université Paul Sabatier, Toulouse, France

11. Service d'Hématologie, Institut Universitaire du Cancer de Toulouse Oncopole, Centre Hospitalier Universitaire de Toulouse, Toulouse, France

12. Université Grenoble Alpes, CNRS, Centre Hospitalier Universitaire Grenoble, Grenoble INP Institute of Engineering Univ. Grenoble Alpes, TIMC-IMAG, Grenoble, France

13. Unité de Parasitologie-Mycologie, Département de Microbiologie, Centre Hospitalier Universitaire Henri Mondor, AP-HP, Créteil, France

14. Service d'Hématologie Clinique, Centre Hospitalier Universitaire, Besançon, France

Abstract

Early diagnosis and treatment are essential to improving the outcome of mucormycosis. The aim of this retrospective study was to assess the contribution of quantitative PCR detection of Mucorales DNA in bronchoalveolar lavage fluids for early diagnosis of pulmonary mucormycosis.

Funder

French Ministry of Health

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00289-18

Reference24 articles.

1. A Global Analysis of Mucormycosis in France: The RetroZygo Study (2005-2007)

2. The Reversed Halo Sign: Pathognomonic Pattern of Pulmonary Mucormycosis in Leukemic Patients With Neutropenia?

3. Is It Time to Include CT “Reverse Halo Sign” and qPCR Targeting Mucorales in Serum to EORTC-MSG Criteria for the Diagnosis of Pulmonary Mucormycosis in Leukemia Patients?