Host Retromer Protein Sorting Nexin 2 Interacts with Human Respiratory Syncytial Virus Structural Proteins and is Required for Efficient Viral Production-Reference-Cited by-同舟云学术

Host Retromer Protein Sorting Nexin 2 Interacts with Human Respiratory Syncytial Virus Structural Proteins and is Required for Efficient Viral Production

Published:2020-10-27 Issue:5 Volume:11 Page:
ISSN:2161-2129
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Cardoso Ricardo S.¹^ORCID,Tavares Lucas Alves¹^ORCID,Jesus Bruna Lais S.¹,Criado Miria F.¹^ORCID,de Carvalho Andreia Nogueira¹,Souza Juliano de Paula¹,Bedi Sukhmani²,de Souza Marcos Michel¹,Silva Maria Lucia¹,Lanfredi Guilherme Pauperio³,Vitti Brenda Cristina¹,Scudero Orlando Bonito⁴,Faça Vitor Marcel³,Ono Akira²^ORCID,Ventura Armando M.⁴,daSilva Luis Lamberti P.¹,Arruda Eurico¹^ORCID

Affiliation:

1. Department of Cell and Molecular Biology, University of São Paulo School of Medicine, Ribeirao Preto, Brazil

2. Department of Microbiology and Immunology, University Michigan Medical School, Ann Arbor, Michigan, USA

3. Department of Biochemistry, University of São Paulo School of Medicine, Ribeirao Preto, Brazil

4. Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

Abstract

The present study contributes new knowledge to understand HRSV assembly by providing evidence that nonglycosylated structural proteins M and N interact with elements of the secretory pathway, shedding light on their intracellular traffic. To the best of our knowledge, the present contribution is important given the scarcity of studies about the traffic of HRSV nonglycosylated proteins, especially by pointing to the involvement of SNX2, a retromer component, in the HRSV assembly process.

Funder

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01869-20

Reference46 articles.

1. Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis

2. Collins PL, Karrib RA. 2013. Respiratory syncytial virus and metapneumovirus, p 1086–1123. In Knipe MD, Howley MP (ed), Fields virology, 6th ed. Lippincott Williams & Wilkins, Philadelphia, PA.

3. Identification of a Linear Heparin Binding Domain for Human Respiratory Syncytial Virus Attachment Glycoprotein G

4. The Fusion Glycoprotein of Human Respiratory Syncytial Virus Facilitates Virus Attachment and Infectivity via an Interaction with Cellular Heparan Sulfate

5. Identification of nucleolin as a cellular receptor for human respiratory syncytial virus

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