Chondroitin Sulfate Proteoglycans Are De Facto Cellular Receptors for Human Papillomavirus 16 under High Serum Conditions-Reference-Cited by-同舟云学术

Chondroitin Sulfate Proteoglycans Are De Facto Cellular Receptors for Human Papillomavirus 16 under High Serum Conditions

Published:2022-04-13 Issue:7 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Fons Nathan R.¹^ORCID,Kines Rhonda C.²,Thompson Cynthia D.¹,Day Patricia M.¹,Lowy Douglas R.¹,Schiller John T.¹^ORCID

Affiliation:

1. Laboratory of Cellular Oncology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

2. Aura Biosciences, Cambridge, Massachusetts, USA

Abstract

Heparan sulfate proteoglycans (HSPGs) have previously been identified as primary attachment factors for the initial binding of human papillomaviruses (HPVs) prior to infection. Here, we demonstrate that in vitro , HPV binding to HSPGs is strongly dependent on the surrounding experimental conditions, including the concentration of fetal bovine serum (FBS).

Funder

Center for Cancer Research, NCI

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01857-21

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