Susceptibility of Multiply Antibiotic-Resistant Pneumococci to the New Beta-Lactam Drugs and Rosaramicin

Author:

Landesman Sheldon H.1,Cummings Marinella1,Gruarin Andrea1,Bernheimer Harriet1

Affiliation:

1. Downstate Medical Center, Brooklyn, New York 11203

Abstract

Eight new beta-lactam antibiotics and rosaramicin were tested for their activity against penicillin-susceptible and multiply resistant pneumococci. All of the beta-lactam drugs were 50- to 150-fold less active against the drug-resistant pneumococci when compared with their activity against penicillin-susceptible pneumococci. Rosaramicin activity was similar to that of erythromycin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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