Evidence for production of an enterotoxin and cholera toxin cross-reactive factor by Aeromonas hydrophila

Author:

Chopra A K,Houston C W,Genaux C T,Dixon J D,Kurosky A

Abstract

The enterotoxins produced by Aeromonas hydrophila were examined for biological activity by the rabbit ileal loop and suckling mouse assays, as well as by elongation of CHO cells. Antigenic evaluation of the culture filtrates from various isolates of A. hydrophila was performed by enzyme-linked immunosorbent assay with anti-cholera toxin and anti-Aeromonas enterotoxin. Heat stability data demonstrated the presence of a heat-labile cholera toxin cross-reactive factor and a heat stable non-cholera toxin cross-reactive enterotoxin. The biological activities of both enterotoxins were heat labile at 56 degrees C for 20 min.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference22 articles.

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4. Cloning of enterotoxin gene from Aeromonas hydrophila provides conclusive evidence of production of a cytotonic enterotoxin;Chakraborty T.;Infect. Immun.,1984

5. Studies on Aeromonas and Plesiomonas species isolated from cases of choleraic diarrhea;Chatterjee B. D.;Ind. J. Med. Res.,1972

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